These 3 fasta files are widely used proteomics contaminants. The files are:

  1. crap_gpm.fasta: the common Repository of Adventitious Proteins (cRAP) from the Global Proteome Machine (GPM) organisation.

  2. crap_ccp.fasta: Cambridge Centre for Proteomics' own cRAP fasta database.

  3. crap_maxquant.fasta.gz: MaxQuant's contaminant database.

These files are extracted from the camprotR package and described in the cRAP databases vignette (see References).

These files are added to the MsDataHub package via the corresponding Zenodo repository to raciliate re-use with minimal dependecies and avoid repeated downloaded using caching.

All credit for compiling the fasta files goes to Charlotte Dawson, maintainer of the camprotR package.

References

  • cRAP databases vignette: https://cambridgecentreforproteomics.github.io/camprotR/articles/crap.html

  • cRPA protein sequences (GPM): https://www.thegpm.org/crap/

  • camprotR package: https://cambridgecentreforproteomics.github.io/camprotR/index.html

  • Gatto, L. (2025). Proteomics contaminant databases (1.0). Zenodo. https://doi.org/10.5281/zenodo.15115102

Author

Laurent Gatto